Hyaluronic Acid JUVÉDERM® ULTRA

What is Juvederm?

JUVÉDERM® ULTRA is a range of non-granular consistency hyaluronic acid (HA) based gels – a substance which naturally exists in the skin and helps hydration and volumisation. In our clinic the procedure consists in introducing very easily the injectable JUVÉDERM® ULTRA gels under the skin in order to instantaneously restore the volume of the skin, to smooth and make disappear the facial wrinkles and folds and to redefine the lips. This is a gel of homogenous, non-granular consistency which easily flows into the skin and provides a smooth, natural look and feel. Most of the other dermal filling hyaluronic based materials on the market are made of gels with granular consistency which gives a rough sensation.
The JUVÉDERM® ULTRA range is also the only range of such products which contains 0.3% Lidocaine to significantly reduce the injection pain thus offering an invigorating experience.

What is hyaluronic acid?

Hyaluronic acid (HA) is a natural substance in the body which helps hydration, it adds volume to the skin.
Hyaluronic acid is used for aesthetic treatments and it was also used by doctors for injections in arthritic joints and to help circulation.

HA is an ideal substance for dermal fillers because they offer a natural sensation of the skin and have a long lasting effect. 97,9% of patients have considered that the result obtained with Juvederm Ultra 3 was “excellent” or “good”.

Juvederm is the only family of dermal filer based on HA approved in the USA to correct moderate to severe wrinkles and folds for up to a year. Furthermore, 75% of patients have preserved a level of improvement of 1 grade or more for up to a year.


The younger you look, the better you feel. But getting old is a process that cannot be stopped and, as the body gets older, the look and the qualities of the skin change.

Age, hormones, sun exposure, smoking – they all have their part leading to wrinkle formation. The skin is more fragile and less elastic. As we get older, the quantity of hyaluronic acid (HA) in the skin – which is very important for water retention – decreases. The glands that produce sebum (sebaceous) become less active and the skin becomes drier.

Besides all these changes, gravity acts as well by pulling the skin down and causing it to sag. Wrinkles are the consequence of the process of aging. With age, cells divide slowlier and the internal layer, called dermis, gets thinner. The elastin network (the protein which offers to the skin its stretching degree) and the collagen fibers (the main supportive proteins of the skin), which support the superficial layers, become weaker or break (they slide one over the other) and may cause wrinkles (seen on the surface).

The wrinkles between the eyebrows (frownlines) and the wrinkles at the corners of the eyes (also called crow’s feet) are formed because of the contractions of the facial muscles. Laughter, frowning, squinting and other usual facial expressions cause the accentuation of the wrinkles. In time, these expressions associated with gravity contribute to the appearance of the double chin and may cause the skin around the eyes to sag.

Exposure to ultraviolet radiation may determine the premature aging of the skin. The premature aging of the skin is called photoaging. Ultraviolet rays, which cause photoaging, destroy the collagen fibers and cause the excessive forming of altered (abnormal) elastin. When the ultraviolet rays destroy the cutaneous tissues, an enzyme called metalloproteinase is produced.
This enzyme generates and resynthesizes new collagen. Wrinkles are formed when the reconstruction process takes place continuously. Healthy skin permanently regenerates itself. While the old collagen is being destroyed, new collagen is being formed. Scientists have noticed that smoking causes an accentuated decrease of collagen production. This fact determines on its turn wrinkle formation.


Juvéderm ® Ultra SMILE has a unique formula, it is designed for immediate results. It is not a secret that lips are an important part of the beauty of the face

If a friendly simle, a kiss, make the face get an expression fast, lips always draw attention on themselves! Beauty may vary from culture to culture, but there are some common landmarks. Studies show that in almost all cultures, full and well defined lips are considered attractive. Actually, full lips are associated with youth and beauty everywhere.
If yoy have always wanted a large smile and soft lips, Juvéderm ® Ultra SMILE can be the answer that you have been looking for. Also, the contour, the defining, the global shape of your lips can be improved in this way.

Juvéderm ® Ultra SMILE is the first filling product, dedicated to lips, which has in its composition an anaesthetic formula with local and immediate effect for extra comfort.
As an effect of aging, even the few lucky ones who were born with perfect lips, may consider the improvement of the appearance of their lips. Over time, the volume of the lips reduces and they seem thinner, flatter. Wrinkles and fine lines will compromise their smooth and well defined look. Around the mouth, the area between the upper lip and the nose may become flat, the corners of the mouth may sag, creating a tired, old look. Juvéderm ® Ultra SMILE – helps to fight the aging signs by giving back the texure and the fineness of the lips, by filling the lines and wrinkles caused by smoking. Juvéderm ® Ultra SMILE adds volume to the lips for a fresh and natural look.
Lips can say many things, even when words cannot. The look of the lips may affect the entire expression of the face.

Juvéderm ® Ultra SMILE works in several ways to offer naturalness, beautiful and long lasting results
The treatment with Juvéderm ® Ultra Smile brings a smile on your lips. Ultra Smile offers to the lips a clear shape, defines them well by improving their contour. With Juvederm Ultra Smile the lips acquire a full, natural and smooth look.


For more comfort, unlike other HA based filling solutions for lips, Juvéderm ® Ultra Smile is the first formula with lidocaine, a local anaesthetic for extra comfort.

Juvéderm ® Ultra Smile has in its composition, for extra comfort, lidocaine – an anaesthetic with local effect.
Also, you can ask us to supplementarily use, anaesthetic cream to ensure the most comfortable treatment possible. As an effect, the anaesthetic gives a slight numbness and a slight itching sensation in the area where it has been injected. The current treatment lasts about 30 minutes.
After Juvéderm ® Ultra Smile is injected, the doctor massages the injected area to ensure a good distribution and applies ice on the area that has been treated for at least 10 minutes, to remove the possibility of ecchymoses and inflammation production. Immediately after the treatment, you may have some colour changes, temporary bruises or edemas in the injected area. There are no specific food restrictions after the treatment.

During the following 24 hours after the injection:
If needed use painkillers depending on the doctor’s recommendation.
It is not recommended to have dental works done immediately after the treatment with Juvéderm® ULTRA SMILE . Ask which facial products or lip balms should be avoided after the treatment.

For how long are the effects of the treatment with Juvéderm ® Ultra SMILE visible?
Juvéderm ® Ultra SMILE has a unique formula which is designed for results which last. The studies made in the USA show that over 78% of the treated persons have noticed an improvement and a persistant effect for more than a year after one treatment!


Effects duration may depend on age, the quantity of the injected filler, the place of injection, the quality of the skin and, generally, on the patient’s health condition and lifestyle. However, with the help of the Juvéderm ULTRA® range, the beneficent effects last for up to a year since the application of the treatment.

After injection, there may occur:

  • reddening
  • swelling and bruising around the area of injection

Most side effects are mild or moderate and disappear after a few days; they include, but are not limited to:

  • pain/sensitivity
  • hardening/ swelling
  • bumps / swelling
  • bruises
  • pruritis
  • discoloration

In the case of any injection procedure, there is also the risk of infection.



We advise you to avoid aspirin or other nonsteroidal and anti-inflammatory drugs (with analgesic, antipyretic and anti-inflammatory effect) for a few days before having JUVEDERM ULTRA injected. It will reduce the risk of bruising and bleeding of the injected area. In case this is your first visit, you will have to inform us beforehand regarding your medical record or any current problems, as well as the allergies that you have to the administered medication.

An allergy test is not necessary unless the doctos considers it necessary.
The procedure is fast and easy. The injection takes only 15-20 minutes.


Because the injectable gel Juvederm ULTRA involves a simple, non-surgical treatment, there is a minimum recovery period.

In the first 24 hours after the treatment, you must avoid:

  • soliciting workout
  • excessive exposure to sun or heat
  • alcoholic drinks to reduce to the minimum the risk of temporary reddening, swelling and/or itching

No treatment can stop the process of aging; you will need rectifications if you want to maintain the effect, so ask us when a new session is recommended.

 In order to help you keep track of the treatments, you will receive the Juvederm ULTRA beauty passport.